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New Monitoring Strategy for the Quality Control in the Processing Practice of Scutellariae Radix

Author(s):

Lili Li, Chunsong Cheng, Qi Huang, Daiyin Peng* and Cun Zhang*   Pages 1 - 10 ( 10 )

Abstract:


Background: Scutellariae Radix (Huangqin) is usually processed into 3 products for different clinical practices. However, a simple analytical method for quality control was rarely reported to quickly estimate the degree of its processing or distinguish different processed products or unqualified ones.

Objective: To study a new strategy for the quality control in the processing practice of Huangqin.

Method: Seven kinds of flavonoids that mainly existed in Huangqin were determined by HPLC-DAD. Chromatographic fingerprints were established to study the variation and discipline of the 3 processed products of Huangqin. PCA and OPLS-DA was used to classify different processed products of Huangqin.

Results: The results showed that baicalin and wogonoside were the main components in the crude and the alcohol Huangqin herb while baicalein and wogonin were mainly existed in carbonized Huangqin. The results of mathematical statistics revealed that processing techniques can make the quality of medicinal materials more uniform.

Conclusion: This multivariate monitoring strategy is suitable for the quality control in processing practice of Huangqin.

Keywords:

Huangqin; processing, quality control, fingerprints, flavonoids, HPLC

Affiliation:

College of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230001, Faculty of Chinese Medicine, Macau University of Science and Technology, Macau 999078, College of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230001, College of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230001, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700



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