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Ionic Liquids, Microextraction Methods and Capillary Electrophoresis in Biomedical Research

[ Vol. 18 , Issue. 1 ]

Author(s):

Natalia Miękus*, Martyna Ceraficka, Marta Chyła, Aleksandra Durska and Tomasz Bączek   Pages 55 - 62 ( 8 )

Abstract:


The review aims to present the importance of implementing microextraction-, capillary electrophoresis- and ionic liquid-based approaches in biomedical research. These analytical strategies could improve the biochemical diagnosis of various life-threatening diseases, aid in the search for therapeutic agents, and discover drug targets. They could be used when designing newer, safer medicinal products. All the proposed analytical approaches meet the requirements of “green chemistry”- based methods, which is relevant nowadays in view of the pollution of the Earth becoming a severe problem. The review is divided into three main sections, and biomedical examples of the application of each presented approach are discussed. It is assumed that the undoubted advantages of ionic liquid-, microextraction- and capillary electrophoresis-based methods will speed up their use in the study of various clinically important analytes from different biological fluids and tissue samples.

Keywords:

Biological samples, biomarkers, capillary electrophoresis, green chemistry, ionic liquids, microextraction

Affiliation:

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, al. Gen. J. Hallera 107, 80-416 Gdańsk, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, al. Gen. J. Hallera 107, 80-416 Gdańsk, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, al. Gen. J. Hallera 107, 80-416 Gdańsk, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, al. Gen. J. Hallera 107, 80-416 Gdańsk, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, al. Gen. J. Hallera 107, 80-416 Gdańsk



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