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Past, Present and Future of Electroanalytical Sensor for Aspirin, Ibuprofen and Paracetamol Detection

Author(s):

Xuejiao Li, Jian Kang*, Hong Ji, Ping Gong and Nan Li   Pages 1 - 11 ( 11 )

Abstract:


Background: Pain not only affects quality of life but can also lead to people suffering from mental illness due to the lack of effective treatment for long-term pain. Analgesics refer to drugs that can partially or completely relieve pain, including non-steroidal anti-inflammatory drugs and central analgesics.

Methods: In recent years, the cross integration of electrochemical analysis technology with biochemistry, materials science, biomedicine and other disciplines has driven the vigorous development of electrochemical sensing technology in the field of life sciences. The electrochemical sensor has many advantages, such as simple equipment, good specificity, high sensitivity, economy and convenience. As a newly emerging technology, electrochemical sensing technology is increasingly widely used in drug analysis.

Results: This review introduces the recent advances of the detection of analgesics using electrochemical technology. We deliberately selected three representative drugs for discussion: aspirin, ibuprofen and paracetamol.

Conclusion: Electrochemical sensing technology has the advantages of high sensitivity, a low detection limit and simple operation. However, sensors still have some technical problems, such as the existence of many interference factors in actual samples in blood drug concentration monitoring and the need for the further optimization of the method conditions for multi-channel detection. With the continuous advancement of research, the application of new detection methods, nanomaterials, and biomolecules has enabled electrochemical technology to make certain progress in the field of drug analysis. In particular, the emergence of new nanomaterials will greatly promote the development of electrochemical sensing technology in drug analysis. As a cutting-edge technology, electrochemical sensing technology has enormous potential application value.

Keywords:

Electrochemical sensors, Analgesics, Aspirin, Ibuprofen, Paracetamol

Affiliation:

Department of Emergency, The First Affiliated Hospital of Dalian Medical University, Dalian 116001, Department of Emergency, The First Affiliated Hospital of Dalian Medical University, Dalian 116001, Department of Pediatrics, The First Affiliated Hospital of Dalian Medical University, Dalian 116001, Department of Emergency, The First Affiliated Hospital of Dalian Medical University, Dalian 116001, Department of Emergency, The First Affiliated Hospital of Dalian Medical University, Dalian 116001



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